Health Evidence Bulletins - Wales: Questions to
assist with the critical appraisal of a systematic review
[including at least one randomised controlled trial] (Type I evidence);
[including at least one non-randomised intervention study] (Type III evidence); or
[of observational studies] (Type IV evidence)
Adapted from the CASP questions (taken from Oxman AD et al. Users' guides to the medical literature. VI How to use an overview. Journal of the American Medical Association. 1994; 272(17): 1367-1371) and Barker, JM. Project for the enhancement of the Welsh Protocols for Investment in Health Gain. Project Methodology. Cardiff: Duthie Library. UWCM, 1996.
A/ What is this review about and can I trust it.
|1. Is the review relevant to the needs of the Project?||continue||discard|
|2. Did the review address a
clearly focused issue?
in terms of:
|3. Did the authors look for
the appropriate sort of papers?
Did the studies address the review's question and have an appropriate study design?
Is it worth continuing?
|4. Were the important,
relevant studies included?
|5. Did the authors assess the quality (rigour) of the included studies?|
|6. If the results of the
review have been combined, was this reasonable?
B/ What did they find?
|7. What is the overall result
of the review?
Include a numerical result with the confidence limits if available.
C/ Are the results relevant locally/to me?
|8. Can the results be
applied to the local population?
|9. Were all important outcomes considered?|
|10. Is any information
provided which could help you decide whether the benefits are worth the harms/costs
(financial and otherwise)?
Summarise the cost information below, if available:
|11. Accept for further use as Type I, III or IV evidence?||Refer to Team Leader|
Draft Statement (if appropriate):
(Remember to include the relevant target group (age range, sex etc.); the measured outcomes/benefits with quantitative information if available; and the Health gain notation)